Modeling αSyn Pathology in Experimental Models
| Thursday, April 10, 2025 |
| 4:30 PM - 6:25 PM |
Overview
Moderator: Jia-Yi Li, Department of Experimental Medical Science, Lund University
Alpha-synuclein in Lewy Bodies
Virginia M-Y Lee, The John H. Ware 3rd Endowed Professor in Alzheimer's Research, Director, Centre for Neurodegenerative Disease Research, University of Pennsylvania
Experimental models of MSA
Nadia Stefanova, Professor at Department of Neurology, Medical University of Innsbruck, Austria
Alpha-synuclein causes tau-dependent synaptic deficits: Mechanistic insights for Lewy body dementia
Michael Lee, Center for Neurodegenerative Disease, Institute for Translational Neuroscience, The University of Minnesota
Selected Abstracts:
Network analysis of α-synuclein progression identifies p21-activated kinases as therapeutic targets for Parkinson’s disease
Michael Henderson, Van Andel Institute
Intranasally administered exosomes containing α-synuclein induce behavioural deficits and brain pathology in vivo but are protected by heterozygous Drp1 knockout
Harry Brown, Florida International University
Diabetes-Driven Neurodegeneration: IDE Deficiency and High-Fat Diet as Key Contributors to Parkinson’s Disease Neuropathology
Hugo Vincente Miranda, NOVA University Lisbon
Panel Discussion
Speaker
Dr. Jia-Yi Li
Professor
Lund University
MODELLING αSyn PATHOLOGY IN EXPERIMENTAL MODELS
4:30 PM - 6:25 PM
Professor Virginia Man-Yee Lee
The John H. Ware 3rd Endowed Professor in Alzheimer's Research, Director
Centre for Neurodegenerative Disease Research, University of Pennsylvania
Alpha-synuclein in Lewy Bodies
4:30 PM - 4:50 PM
Prof. Dr. Nadia Stefanova
Professor of Translational Neurodegeneration Research, Director of Division of Neurobiology
Medical University of Innsbruck
Experimental models of MSA
4:50 PM - 5:10 PM
Dr. Michael Lee
Professor
University Of Minnesota
Alpha-synuclein causes tau-dependent synaptic deficits: Mechanistic insights for Lewy body dementia
5:10 PM - 5:30 PM
Dr. Michael Henderson
Associate Professor
Van Andel Institute
Network analysis of α-synuclein progression identifies p21-activated kinases as therapeutic targets for Parkinson’s disease
5:40 PM - 5:52 PM
Mr Harry J Brown
Phd Student
Florida International University
Intranasally administered exosomes containing α-synuclein induce behavioural deficits and brain pathology in vivo but are protected by heterozygous Drp1 knockout
5:52 PM - 6:04 PM
Prof. Hugo Vicente Miranda
Principal Investigator
Nova Medical School, Universidade Nova De Lisboa
Diabetes-Driven Neurodegeneration: IDE Deficiency and High-Fat Diet as Key Contributors to Parkinson’s Disease Neuropathology
6:04 PM - 6:16 PM
