αSyn Biomarkers SAA
| Thursday, April 10, 2025 |
| 2:15 PM - 4:00 PM |
Overview
Moderator: Evangelia Emmanouilidou, National and Kapodistrian University of Athens
Alpha-synucelin seed amplification assay: Applications for diagnosis, drug discovery and to understand disease mechanisms
Claudio Soto, Professor, University of Texas Medical School
Selected Abstracts:
Quantitative Measurements of α-Synuclein Seeds in CSF Inform Diagnosis and Staging of Synucleinopathies
Omar El-Agnaf, Qatar Biomedical Research Institute, HBKU, Qatar Foundation
Single extracellular vesicle detection assay identifies membrane-associated a-Synuclein as an early-stage biomarker in Parkinson’s disease
Shijun Yan, University of Oxford
Brain-derived and in vitro-seeded alpha-synuclein fibrils exhibit distinct biophysical profiles Laura Parkkinen, University of Oxford
Structural insight into binding of novel PET tracer MODAG-005 to lipidic 𝛼-Synuclein fibrils
Myeongkyu Kim, Max Planck Institute for Multidisciplinary Sciences
Dual 4R-Tau and α-Synuclein Seed Amplification Assays for Differential Diagnosis of Movement Disorders
Ivan Martinez-Valbuena, Tanz Centre for Research in Neurodegenerative diseases - University of Toronto
Panel Discussion
Speaker
Dr Evangelia Emmanouilidou
Assistant Professor
National and Kapodistrian University of Athens
αSyn BIOMARKERS SAA
2:15 PM - 4:00 PM
Professor Claudio Soto
University of Texas Medical School
Alpha-synucelin seed amplification assay: Applications for diagnosis, drug discovery and to understand disease mechanisms
2:15 PM - 2:35 PM
Dr Omar El-Agnaf
Pi
Qatar Biomedical Research Institute, HBKU, Qatar Foundation
Quantitative Measurements of α-Synuclein Seeds in CSF Inform Diagnosis and Staging of Synucleinopathies
2:35 PM - 2:47 PM
Mr Shijun Yan
Dphil Student
University Of Oxford
Single extracellular vesicle detection assay identifies membrane-associated a-Synuclein as an early-stage biomarker in Parkinson’s disease
2:47 PM - 2:59 PM
Professor Laura Parkkinen
Professor of Translational Neuropathology, Director of the Oxford Brain Bank
University of Oxford
Brain-derived and in vitro-seeded alpha-synuclein fibrils exhibit distinct biophysical profiles
2:59 PM - 3:11 PM
Dr. Myeongkyu Kim
Postdoctoral Researcher
Max Planck Institute For Multidisciplinary Sciences
Structural insight into binding of novel PET tracer MODAG-005 to lipidic 𝛼-Synuclein fibrils
3:11 PM - 3:22 PM
Dr Ivan Martinez-Valbuena
University Of Toronto
Dual 4R-Tau and α-Synuclein Seed Amplification Assays for Differential Diagnosis of Movement Disorders
3:22 PM - 3:34 PM
