αSyn Clearance Mechanisms
| Friday, April 11, 2025 |
| 10:00 AM - 12:00 PM |
Overview
Moderator: Darren Moore, Department of Neurodegenerative Science, Van Andel Institute
The role of the serine peptidase KLK6 in extracellular alpha-synuclein clearance. Kostas Vekrellis, Research Director, Biomedical Research Foundation Academy of Athens and Visiting Professor, Dept. Of Experimental Medicine, University of Oxford
Therapeutic Potential of the Glymphatic System in the Clearance of Pathological α-Synuclein
Ian Harrison, Principal Research Fellow, University College London
Regulation of α-Synuclein accumulation in cells
Edward, Fon, Scientific Director, Montreal Neurological Institute-Hospital
Selected Abstracts:
Astrocytic degradation pathway disruption and secretome alterations in α-synuclein pathology: implications for dopaminergic neuronal health and function
Indrani Datta, National Institute of Mental Health and Neurosciences (NIMHANS)
Inducing Chaperone-Mediated Autophagy as a Means to Counteract alpha-Synuclein Pathology in Non-Human Primates
Maria Fouka, BRFAA - Biomedical Research Foundation Academy of Athens
Determining how Parkinson’s disease risk genes influence α-synuclein pathology and clearance Cara Croft, Queen Mary University of London
Panel Discussion
Speaker
Dr. Darren Moore
Professor and Chair
Van Andel Institute
αSyn CLEARANCE MECHANISMS
9:30 AM - 11:30 AM
Dr Vekrellis Kostas
Research Director
Biomedical Research Foundation Academy of Athens, Greece
The role of the serine peptidase KLK6 in extracellular alpha-synuclein clearance.
10:00 AM - 10:20 AM
Dr Ian Harrison
Principal Research Fellow
University College London
Therapeutic Potential of the Glymphatic System in the Clearance of Pathological α-Synuclein
10:20 AM - 10:40 AM
Professor Edward Fon
Professor and Scientific Director
Montreal Neurological Institute-Hospital, McGill University
Regulation of α-Synuclein accumulation in cells
10:40 AM - 11:00 AM
Dr Indrani Datta
Additional Professor
National Institute Of Mental Health And Neurosciences (NIMHANS)
Astrocytic degradation pathway disruption and secretome alterations in α-synuclein pathology: implications for dopaminergic neuronal health and function
11:00 AM - 11:12 AM
Dr Maria Xilouri
Assistant Professor
Biomedical Research Foundation of The Academy Of Athens
Inducing Chaperone-Mediated Autophagy as a Means to Counteract alpha-Synuclein Pathology in Non-Human Primates
11:12 AM - 11:24 AM
Dr Cara Croft
Senior Lecturer/Group Leader
Queen Mary University Of London
Determining how Parkinson’s disease risk genes influence α-synuclein pathology and clearance
11:24 AM - 11:36 AM
