αSyn Spreading and Periphery

Thursday, April 10, 2025
11:00 AM - 12:55 PM

Overview


Moderator: Ayse Ulusoy, Group Leader, German Center for Neurodegenerative Diseases

T-cells and gut macrophages as modulators in body-first Parkinson’s Disease
Tim Bartels, Group Leader, UK Dementia Research Institute; Associate Professor, University College London

Oxidative/nitrative stress promotes alpha-synuclein spreading in vivo
Donato A. Di Monte, Senior Group Leader, German Center for Neurodegenerative Diseases (DZNE)

Modeling alpha-synuclein propagation and neurotoxicity in rodent brain
Veerle Baekelandt, Professor, KU Leuven

Selected Abstracts:
Alpha-synuclein prion strains differentially adapt after passage in mice
Amanda Woerman, Colorado State University

Periphery to brain spreading of a-syn in novel PD mouse models
Pauline Vessiere, University of Cambridge

Molecular signatures of altered energy metabolism and circadian rhythm perturbations in a model of alpha-Synucleinopathy
Asad Jan, Aarhus University, Denmark

Panel Discussion


Speaker

Dr Ayse Ulusoy
Group Leader
German Center for Neurodegenerative Diseases

αSyn SPREADING AND PERIPHERY

11:00 AM - 12:55 PM
Kendra Frederick
Assistant Professor
Ut Southwestern Medical Center

In cell NMR reveals cells selectively amplify and structurally remodel amyloid fibrils

12:12 PM - 12:24 PM
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Prof. Tim Bartels
Associate Professor UCL / Group Leader UK Dementia Research Institute, Associate Professor at University College London
University College London

T-cells and gut macrophages as modulators in body-first Parkinson’s Disease

11:00 AM - 11:20 AM
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Dr Donato Di Monte
Professor and Senior Group Leader
German Center for Neurodegenerative Diseases

Oxidative/nitrative stress promotes alpha-synuclein spreading in vivo

11:20 AM - 11:40 AM
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Professor Veerle BAEKELANDT
Full Professor
KU Leuven

Modeling alpha-synuclein propagation and neurotoxicity in rodent brain

11:40 AM - 12:00 PM
Dr. Amanda Woerman
Associate Professor
Colorado State University

Alpha-synuclein prion strains differentially adapt after passage in mice

12:00 PM - 12:12 PM
Miss Pauline Vessiere
PhD Student
University Of Cambridge

Periphery to brain spreading of a-syn in novel PD mouse models

12:12 PM - 12:24 PM
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Dr Asad Jan
Assistant Professor
Aarhus University

Molecular signatures of altered energy metabolism and circadian rhythm perturbations in a model of alpha-Synucleinopathy

12:24 PM - 12:36 PM
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