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Physiology and Interactome

Tracks
West Road Concert Hall
Wednesday, April 9, 2025
8:30 AM - 10:00 AM

Overview


Moderator: Pam McLean, Mayo Clinic

VAMP2 regulates alpha-synuclein phase separation
Janin Lautenschlaeger, Principal Investigator and Royal Society Dorothy Hodgkin Research Fellow, Cambridge Institute for Medical Research (CIMR), University of Cambridge

Selected abstracts:
Distinguishing α-synuclein serine-129 phosphorylation in health and Lewy body diseases
Nagendran Ramalingam, Brigham & Women's Hospital and Harvard Medical School

G6PD deficiency triggers dopamine loss and the initiation of Parkinson’s Disease pathogenesis
Scott Ryan, University of Calgary

A new paradigm for investigating synucleinopathy therapeutic targets and biomarkers: approaching synucleinopathies as lipidopathies.
Saranna Fanning, Harvard Medical School and Brigham & Women's Hospital

Lipidomic Profiling Reveals Shared and Distinct Pathological Signatures in Sporadic Parkinson's Disease and GBA Mutation Carriers
Céline Galvagnion, University of Copenhagen

Panel Discussion


Speaker

Dr Pam McLean
Professor
Mayo Clinic

PHYSIOLOGY AND INTERACTOME

8:30 AM - 10:00 AM
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Dr. Janin Lautenschlaeger
Principal Investigator and Royal Society Dorothy Hodgkin Research Fellow, Cambridge Institute for Medical Research (CIMR)
University of Cambridge

VAMP2 regulates alpha-synuclein phase separation

8:30 AM - 8:50 AM
Dr Nagendran Ramalingam
Assistant Professor
Brigham & Women's Hospital And Harvard Medical School

Distinguishing α-synuclein serine-129 phosphorylation in health and Lewy body diseases

8:50 AM - 9:02 AM
Dr. Scott Ryan
Associate Professor
University Of Calgary

G6PD deficiency triggers dopamine loss and the initiation of Parkinson’s Disease pathogenesis

9:02 AM - 9:14 AM
Dr. Saranna Fanning
Assistant Professor
Harvard Medical School, Brigham & Women's Hospital

A new paradigm for investigating synucleinopathy therapeutic targets and biomarkers: approaching synucleinopathies as lipidopathies.

9:14 AM - 9:26 AM
Agenda Item Image
Dr Céline Galvagnion
Associate Professor
University Of Copenhagen

Lipidomic Profiling Reveals Shared and Distinct Pathological Signatures in Sporadic Parkinson's Disease and GBA Mutation Carriers

9:26 AM - 9:38 AM
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