αSyn and Organelle Homeostasis
| Wednesday, April 9, 2025 |
| 1:20 PM - 3:15 PM |
Overview
Moderator: Poul Henning Jensen
Parkinson’s Disease Revisited: A Disorder of Proteins, Organelles, or an Interplay of Both?
Hilal Lashuel, Director of the Laboratory of Chemical Biology of Neurodegeneration, Swiss Federal Institute of Technology Lausanne
Interplay between α-Synuclein and organelle homeostasis at the onset of Parkinson’s disease
George Tofaris, Professor of Neurology and Translational Neuroscience, University of Oxford
The dynamic cellular biology of alpha-synuclein
Ulf Dettmer, Associate Professor of Neurology, Harvard Medical School
Ann Romney Center for Neurologic Diseases Brigham and Women’s Hospital
Selected Abstracts:
Alpha-synuclein regulates the neuronal lipidome in synucleinopathies at the Mitochondria-Associated ER Membranes (MAM)
Peter Barbuti, Columbia University
Pharmacological correction of excessive basal mitophagy by pathological levels of α-synuclein restores neuronal function in human dopaminergic neurons
Elliot Mock, University of Oxford
A novel pathway underlying the dysregulation of alpha-synuclein in Parkinson’s disease
Eleanna Kara, Rutgers University
Panel Discussion
Speaker
Professor Poul Henning Jensen
Professor
Aarhus University
αSyn AND ORGANELLE HOMEOSTASIS
1:20 PM - 3:15 PM
Professor Hilal Lashuel
Research, Development and Innovation Advisor to the Chairperson of Qatar Foundation and Executive Director of RDI
Qatar Foundation
Parkinson’s Disease Revisited: A Disorder of Proteins, Organelles, or an Interplay of Both?
1:20 PM - 1:40 PM
Professor George Tofaris
Professor of Neurology and Translational Nesuroscience
University of Oxford
Interplay between α-Synuclein and organelle homeostasis at the onset of Parkinson’s disease
1:40 PM - 2:00 PM
Dr Ulf Dettmer
Associate Professor of Neurology
Harvard Medical School Ann Romney Center for Neurologic Diseases Brigham and Women’s Hospital
The dynamic cellular biology of alpha-synuclein
2:00 PM - 2:20 PM
Dr Peter Barbuti
Associate Research Scientist
Columbia University
Alpha-synuclein regulates the neuronal lipidome in synucleinopathies at the Mitochondria-Associated ER Membranes (MAM)
2:20 PM - 2:32 PM
Dr Elliot Mock
Postdoctoral Research Scientist
University of Oxford
Pharmacological correction of excessive basal mitophagy by pathological levels of α-synuclein restores neuronal function in human dopaminergic neurons
2:32 PM - 2:44 PM
Dr Eleanna Kara
Assistant Professor
Rutgers University
A novel pathway underlying the dysregulation of alpha-synuclein in Parkinson’s disease
2:44 PM - 2:56 PM
